Drug interactions
Insulin degludec-liraglutide + Methyltestosterone
Severity: Moderate
Insulin degludec-liraglutide and Methyltestosterone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgens can improve insulin sensitivity and lower blood glucose, which may add to the effect of insulin degludec/liraglutide. Hypoglycemia is possible, especially at the start of androgen therapy or with dose increases.
What this interaction means in plain words
Insulin degludec-liraglutide and Methyltestosterone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Androgens may enhance insulin sensitivity and glucose utilization, producing an additive glucose-lowering effect.
What to do
Monitor blood glucose when methyltestosterone is started or changed. Reduce the insulin degludec dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Insulin degludec-liraglutide and Methyltestosterone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Insulin degludec-liraglutide
Frequently asked questions
Can I take Insulin degludec-liraglutide with Methyltestosterone?
MediHelp rates the interaction as moderate. Insulin degludec-liraglutide and Methyltestosterone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Androgens can improve insulin sensitivity and lower blood glucose, which may add to the effect of insulin degludec/liraglutide. Hypoglycemia is possible, especially at the start of androgen therapy or with dose increases.
How serious is the interaction between Insulin degludec-liraglutide and Methyltestosterone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when methyltestosterone is started or changed. Reduce the insulin degludec dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
