Drug interactions
Insulin degludec-liraglutide + Norgestimate
Severity: Minor
Insulin degludec-liraglutide and Norgestimate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combined oral contraceptives containing norgestimate can modestly impair glucose tolerance. In diabetic patients this may slightly weaken the effect of insulin degludec/liraglutide. The effect is usually small.
What this interaction means in plain words
Insulin degludec-liraglutide and Norgestimate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
The estrogen/progestin combination can reduce insulin sensitivity and glucose tolerance.
What to do
Monitor glycemic control when the contraceptive is started or stopped. Adjust the insulin dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Frequently asked questions
Can I take Insulin degludec-liraglutide with Norgestimate?
MediHelp rates the interaction as minor. Insulin degludec-liraglutide and Norgestimate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Combined oral contraceptives containing norgestimate can modestly impair glucose tolerance. In diabetic patients this may slightly weaken the effect of insulin degludec/liraglutide. The effect is usually small.
How serious is the interaction between Insulin degludec-liraglutide and Norgestimate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glycemic control when the contraceptive is started or stopped. Adjust the insulin dose if needed.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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