Drug interactions
Insulin degludec-liraglutide + Olmesartan
Severity: Minor
Insulin degludec-liraglutide and Olmesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may improve insulin sensitivity and slightly increase the hypoglycemic effect of insulin. Hypoglycemia is uncommon but may occur after the ARB is started.
What this interaction means in plain words
Insulin degludec-liraglutide and Olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Insulin degludec-liraglutide belongs to Endocrine; Olmesartan belongs to Cardiovascular.
Why it happens
ARBs may improve insulin sensitivity, adding to the glucose-lowering effect.
What to do
Monitor glucose after starting olmesartan and reduce insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Other interactions of Olmesartan
- Aliskiren + Olmesartan Contraindicated
- Olmesartan + Sparsentan Contraindicated
- Aldesleukin + Olmesartan Major
- Amifostine + Olmesartan Major
- Amiloride + Olmesartan Major
- Amlodipine-benazepril + Olmesartan Major
Frequently asked questions
Can I take Insulin degludec-liraglutide with Olmesartan?
MediHelp rates the interaction as minor. Insulin degludec-liraglutide and Olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may improve insulin sensitivity and slightly increase the hypoglycemic effect of insulin. Hypoglycemia is uncommon but may occur after the ARB is started.
How serious is the interaction between Insulin degludec-liraglutide and Olmesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose after starting olmesartan and reduce insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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