Drug interactions
Insulin degludec-liraglutide + Progesterone micronized
Severity: Minor
Insulin degludec-liraglutide and Progesterone micronized: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral micronized progesterone gives systemic exposure and may modestly impair glucose tolerance. This could slightly reduce the effect of insulin degludec/liraglutide.
What this interaction means in plain words
Insulin degludec-liraglutide and Progesterone micronized have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Progestogens may reduce insulin sensitivity, mildly opposing antidiabetic therapy.
What to do
Monitor blood glucose when progesterone is started or stopped. Adjust the insulin dose if glucose control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Frequently asked questions
Can I take Insulin degludec-liraglutide with Progesterone micronized?
MediHelp rates the interaction as minor. Insulin degludec-liraglutide and Progesterone micronized have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral micronized progesterone gives systemic exposure and may modestly impair glucose tolerance. This could slightly reduce the effect of insulin degludec/liraglutide.
How serious is the interaction between Insulin degludec-liraglutide and Progesterone micronized?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when progesterone is started or stopped. Adjust the insulin dose if glucose control changes.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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