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Drug interactions

Insulin degludec-liraglutide + Testosterone intranasal

Severity: Minor

Insulin degludec-liraglutide and Testosterone intranasal: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Testosterone may improve insulin sensitivity and lower blood glucose, which can add to the effect of insulin degludec and liraglutide and occasionally cause hypoglycemia.

What this interaction means in plain words

Insulin degludec-liraglutide and Testosterone intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Androgens may increase insulin sensitivity and glucose uptake.

What to do

Monitor blood glucose after starting testosterone and reduce the antidiabetic dose if hypoglycemia occurs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Insulin degludec-liraglutide with Testosterone intranasal?

MediHelp rates the interaction as minor. Insulin degludec-liraglutide and Testosterone intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Testosterone may improve insulin sensitivity and lower blood glucose, which can add to the effect of insulin degludec and liraglutide and occasionally cause hypoglycemia.

How serious is the interaction between Insulin degludec-liraglutide and Testosterone intranasal?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting testosterone and reduce the antidiabetic dose if hypoglycemia occurs.

What other medicines interact with Insulin degludec-liraglutide?

MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.

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