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Drug interactions

Insulin glargine-lixisenatide + Maitake

Severity: Minor

Insulin glargine-lixisenatide and Maitake: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Maitake mushroom extracts have lowered blood glucose in animal studies, suggesting a possible additive effect with insulin and lixisenatide. Human data are limited.

What this interaction means in plain words

Insulin glargine-lixisenatide and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive glucose lowering, with improved insulin sensitivity suggested in animal work.

What to do

Check blood glucose more frequently when maitake supplements are started and adjust insulin if hypoglycemia occurs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Insulin glargine-lixisenatide with Maitake?

MediHelp rates the interaction as minor. Insulin glargine-lixisenatide and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom extracts have lowered blood glucose in animal studies, suggesting a possible additive effect with insulin and lixisenatide. Human data are limited.

How serious is the interaction between Insulin glargine-lixisenatide and Maitake?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose more frequently when maitake supplements are started and adjust insulin if hypoglycemia occurs.

What other medicines interact with Insulin glargine-lixisenatide?

MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.

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