Drug interactions
Insulin glargine-lixisenatide + Nettle
Severity: Minor
Insulin glargine-lixisenatide and Nettle: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nettle has reported hypoglycemic activity, so it could theoretically add to the effect of insulin and lixisenatide. Clinical evidence is scant.
What this interaction means in plain words
Insulin glargine-lixisenatide and Nettle have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive hypoglycemic effect; the mechanism is not established.
What to do
Monitor blood glucose when nettle products are started or stopped, and adjust insulin dose if readings change.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin glargine-lixisenatide
- Albiglutide + Insulin glargine-lixisenatide Major
- Chlorpropamide + Insulin glargine-lixisenatide Major
- Dulaglutide + Insulin glargine-lixisenatide Major
- Ethanol + Insulin glargine-lixisenatide Major
- Exenatide injectable + Insulin glargine-lixisenatide Major
- Glimepiride + Insulin glargine-lixisenatide Major
Frequently asked questions
Can I take Insulin glargine-lixisenatide with Nettle?
MediHelp rates the interaction as minor. Insulin glargine-lixisenatide and Nettle have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nettle has reported hypoglycemic activity, so it could theoretically add to the effect of insulin and lixisenatide. Clinical evidence is scant.
How serious is the interaction between Insulin glargine-lixisenatide and Nettle?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when nettle products are started or stopped, and adjust insulin dose if readings change.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
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