Drug interactions
Insulin glargine-lixisenatide + Oxandrolone
Severity: Moderate
Insulin glargine-lixisenatide and Oxandrolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anabolic androgenic steroids can improve insulin sensitivity and lower blood glucose, which may increase hypoglycemia risk in insulin-treated patients. Insulin dose reduction may be needed.
What this interaction means in plain words
Insulin glargine-lixisenatide and Oxandrolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Anabolic steroids enhance insulin sensitivity and glucose utilization, adding to the glucose-lowering effect.
What to do
Monitor blood glucose closely when oxandrolone is started or stopped, and reduce the insulin dose as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin glargine-lixisenatide
- Albiglutide + Insulin glargine-lixisenatide Major
- Chlorpropamide + Insulin glargine-lixisenatide Major
- Dulaglutide + Insulin glargine-lixisenatide Major
- Ethanol + Insulin glargine-lixisenatide Major
- Exenatide injectable + Insulin glargine-lixisenatide Major
- Glimepiride + Insulin glargine-lixisenatide Major
Frequently asked questions
Can I take Insulin glargine-lixisenatide with Oxandrolone?
MediHelp rates the interaction as moderate. Insulin glargine-lixisenatide and Oxandrolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anabolic androgenic steroids can improve insulin sensitivity and lower blood glucose, which may increase hypoglycemia risk in insulin-treated patients. Insulin dose reduction may be needed.
How serious is the interaction between Insulin glargine-lixisenatide and Oxandrolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely when oxandrolone is started or stopped, and reduce the insulin dose as needed.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
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