Drug interactions
Insulin glargine-lixisenatide + Oxymetholone
Severity: Moderate
Insulin glargine-lixisenatide and Oxymetholone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxymetholone, an anabolic steroid, can enhance insulin sensitivity and lower blood glucose, increasing the risk of hypoglycemia with insulin. Dose requirements may fall.
What this interaction means in plain words
Insulin glargine-lixisenatide and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Anabolic steroids enhance insulin sensitivity and glucose utilization, adding to the glucose-lowering effect.
What to do
Monitor blood glucose closely at initiation and discontinuation, and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin glargine-lixisenatide
- Albiglutide + Insulin glargine-lixisenatide Major
- Chlorpropamide + Insulin glargine-lixisenatide Major
- Dulaglutide + Insulin glargine-lixisenatide Major
- Ethanol + Insulin glargine-lixisenatide Major
- Exenatide injectable + Insulin glargine-lixisenatide Major
- Glimepiride + Insulin glargine-lixisenatide Major
Frequently asked questions
Can I take Insulin glargine-lixisenatide with Oxymetholone?
MediHelp rates the interaction as moderate. Insulin glargine-lixisenatide and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxymetholone, an anabolic steroid, can enhance insulin sensitivity and lower blood glucose, increasing the risk of hypoglycemia with insulin. Dose requirements may fall.
How serious is the interaction between Insulin glargine-lixisenatide and Oxymetholone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely at initiation and discontinuation, and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
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