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Drug interactions

Insulin glargine-lixisenatide + Panax ginseng

Severity: Moderate

Insulin glargine-lixisenatide and Panax ginseng: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Panax ginseng has been reported to lower blood glucose and may add to the effects of insulin and lixisenatide. This could increase the risk of hypoglycemia, although product variability makes the effect unpredictable.

What this interaction means in plain words

Insulin glargine-lixisenatide and Panax ginseng can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive glucose lowering, possibly via improved insulin sensitivity and insulin secretion.

What to do

Monitor blood glucose more often when ginseng is started or stopped, and reduce the insulin dose if hypoglycemia occurs.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Insulin glargine-lixisenatide with Panax ginseng?

MediHelp rates the interaction as moderate. Insulin glargine-lixisenatide and Panax ginseng can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Panax ginseng has been reported to lower blood glucose and may add to the effects of insulin and lixisenatide. This could increase the risk of hypoglycemia, although product variability makes the effect unpredictable.

How serious is the interaction between Insulin glargine-lixisenatide and Panax ginseng?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more often when ginseng is started or stopped, and reduce the insulin dose if hypoglycemia occurs.

What other medicines interact with Insulin glargine-lixisenatide?

MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.

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