Drug interactions
Insulin glulisine + Maitake
Severity: Minor
Insulin glulisine and Maitake: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maitake mushroom extracts lowered blood glucose in animal studies. In a patient using insulin glulisine this might add to the insulin effect and increase hypoglycemia risk. Human evidence is lacking.
What this interaction means in plain words
Insulin glulisine and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive glucose-lowering effect of maitake polysaccharides, shown in animal models only.
What to do
Monitor blood glucose more closely when maitake supplements are started. Lower the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin glulisine
Frequently asked questions
Can I take Insulin glulisine with Maitake?
MediHelp rates the interaction as minor. Insulin glulisine and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom extracts lowered blood glucose in animal studies. In a patient using insulin glulisine this might add to the insulin effect and increase hypoglycemia risk. Human evidence is lacking.
How serious is the interaction between Insulin glulisine and Maitake?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more closely when maitake supplements are started. Lower the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin glulisine?
MediHelp also lists interactions of Insulin glulisine with, for example, Alogliptin-pioglitazone, Ethanol, Pentamidine. The full list is on the Insulin glulisine page.
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