Drug interactions
Insulin glulisine + Oxymetholone
Severity: Moderate
Insulin glulisine and Oxymetholone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxymetholone, an anabolic steroid, can improve glucose tolerance and enhance the effect of insulin. This may lead to hypoglycemia in patients on insulin glulisine and dose reductions may be needed.
What this interaction means in plain words
Insulin glulisine and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Anabolic androgenic steroids increase insulin sensitivity and lower blood glucose, adding to the effect of insulin.
What to do
Check blood glucose more often when oxymetholone is started or the dose changed, and reduce the insulin dose as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin glulisine
Frequently asked questions
Can I take Insulin glulisine with Oxymetholone?
MediHelp rates the interaction as moderate. Insulin glulisine and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxymetholone, an anabolic steroid, can improve glucose tolerance and enhance the effect of insulin. This may lead to hypoglycemia in patients on insulin glulisine and dose reductions may be needed.
How serious is the interaction between Insulin glulisine and Oxymetholone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose more often when oxymetholone is started or the dose changed, and reduce the insulin dose as needed.
What other medicines interact with Insulin glulisine?
MediHelp also lists interactions of Insulin glulisine with, for example, Alogliptin-pioglitazone, Ethanol, Pentamidine. The full list is on the Insulin glulisine page.
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