Drug interactions
Insulin isophane protamine human + Telmisartan
Severity: Moderate
Insulin isophane protamine human and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may enhance insulin sensitivity and increase the glucose-lowering effect of insulin, occasionally causing hypoglycemia. The effect is usually modest.
What this interaction means in plain words
Insulin isophane protamine human and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin isophane protamine human belongs to Endocrine; Telmisartan belongs to Cardiovascular.
Why it happens
ARBs may improve insulin sensitivity and peripheral glucose uptake; the exact mechanism is not firmly established.
What to do
Increase glucose monitoring when telmisartan is started and adjust the insulin dose if glucose falls.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin isophane protamine human
- Ethanol + Insulin isophane protamine human Major
- Insulin isophane protamine human + Pioglitazone Major
- Insulin isophane protamine human + Rosiglitazone Major
- Acarbose + Insulin isophane protamine human Moderate
- Albiglutide + Insulin isophane protamine human Moderate
- Alogliptin + Insulin isophane protamine human Moderate
Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Frequently asked questions
Can I take Insulin isophane protamine human with Telmisartan?
MediHelp rates the interaction as moderate. Insulin isophane protamine human and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Angiotensin receptor blockers may enhance insulin sensitivity and increase the glucose-lowering effect of insulin, occasionally causing hypoglycemia. The effect is usually modest.
How serious is the interaction between Insulin isophane protamine human and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Increase glucose monitoring when telmisartan is started and adjust the insulin dose if glucose falls.
What other medicines interact with Insulin isophane protamine human?
MediHelp also lists interactions of Insulin isophane protamine human with, for example, Ethanol, Pioglitazone, Rosiglitazone. The full list is on the Insulin isophane protamine human page.
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