Drug interactions
Interferon beta 1b + Ublituximab
Severity: Moderate
Interferon beta 1b and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ublituximab depletes B cells and interferon beta has immunomodulatory effects, so concurrent use may increase susceptibility to infection. The two are not usually combined, as ublituximab is itself a disease-modifying therapy for multiple sclerosis.
What this interaction means in plain words
Interferon beta 1b and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Interferon beta 1b belongs to Central Nervous System; Ublituximab belongs to Miscellaneous.
Why it happens
Additive immunomodulation from B-cell depletion and interferon-mediated effects.
What to do
Avoid routine combination and stop interferon beta when ublituximab is started; monitor for infection if overlap occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Interferon beta 1b and Ublituximab, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Interferon beta 1b
Other interactions of Ublituximab
Frequently asked questions
Can I take Interferon beta 1b with Ublituximab?
MediHelp rates the interaction as moderate. Interferon beta 1b and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ublituximab depletes B cells and interferon beta has immunomodulatory effects, so concurrent use may increase susceptibility to infection. The two are not usually combined, as ublituximab is itself a disease-modifying therapy for multiple sclerosis.
How serious is the interaction between Interferon beta 1b and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine combination and stop interferon beta when ublituximab is started; monitor for infection if overlap occurs.
What other medicines interact with Interferon beta 1b?
MediHelp also lists interactions of Interferon beta 1b with, for example, Axicabtagene ciloleucel, Brexucabtagene autoleucel, Ciltacabtagene autoleucel. The full list is on the Interferon beta 1b page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
