Drug interactions
Ketorolac + Terazosin
Severity: Minor
Ketorolac and Terazosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ketorolac may blunt the antihypertensive effect of terazosin, and it can also impair renal function in susceptible patients. Courses are short, so the blood pressure effect is usually limited.
What this interaction means in plain words
Ketorolac and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ketorolac belongs to Musculoskeletal; Terazosin belongs to Genitourinary.
Why it happens
NSAID inhibition of prostaglandin synthesis causes sodium and fluid retention and reduced renal perfusion.
What to do
Monitor blood pressure during ketorolac therapy and limit use to the shortest labeled duration.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Frequently asked questions
Can I take Ketorolac with Terazosin?
MediHelp rates the interaction as minor. Ketorolac and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ketorolac may blunt the antihypertensive effect of terazosin, and it can also impair renal function in susceptible patients. Courses are short, so the blood pressure effect is usually limited.
How serious is the interaction between Ketorolac and Terazosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during ketorolac therapy and limit use to the shortest labeled duration.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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