Drug interactions
Ketorolac intranasal + Terazosin
Severity: Moderate
Ketorolac intranasal and Terazosin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ketorolac is absorbed systemically after intranasal use and as an NSAID may reduce the antihypertensive effect of terazosin. Short-course use makes a clinically significant rise in blood pressure less likely.
What this interaction means in plain words
Ketorolac intranasal and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
NSAID inhibition of prostaglandin synthesis causes sodium retention and opposes vasodilation.
What to do
Monitor blood pressure during ketorolac therapy and keep the course short, within labeled limits.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Frequently asked questions
Can I take Ketorolac intranasal with Terazosin?
MediHelp rates the interaction as moderate. Ketorolac intranasal and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ketorolac is absorbed systemically after intranasal use and as an NSAID may reduce the antihypertensive effect of terazosin. Short-course use makes a clinically significant rise in blood pressure less likely.
How serious is the interaction between Ketorolac intranasal and Terazosin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during ketorolac therapy and keep the course short, within labeled limits.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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