Drug interactions
Ketotifen + Scullcap
Severity: Minor
Ketotifen and Scullcap: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Scullcap is a herbal product traditionally used for its calming effects, and ketotifen is a sedating antihistamine. Combined use might increase drowsiness, although the evidence for scullcap sedation is limited.
What this interaction means in plain words
Ketotifen and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive sedation; the herb's sedative mechanism is not well established.
What to do
Advise patients to watch for excess drowsiness and to avoid driving until the combined effect is known.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketotifen
- Ketotifen + Phenobarbital Moderate
- Ketotifen + Pholcodine Moderate
- Ketotifen + Primidone Moderate
- Ketotifen + Protriptyline Moderate
- Ketotifen + Quazepam Moderate
- Ketotifen + Rotigotine Moderate
Frequently asked questions
Can I take Ketotifen with Scullcap?
MediHelp rates the interaction as minor. Ketotifen and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Scullcap is a herbal product traditionally used for its calming effects, and ketotifen is a sedating antihistamine. Combined use might increase drowsiness, although the evidence for scullcap sedation is limited.
How serious is the interaction between Ketotifen and Scullcap?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for excess drowsiness and to avoid driving until the combined effect is known.
What other medicines interact with Ketotifen?
MediHelp also lists interactions of Ketotifen with, for example, Phenobarbital, Pholcodine, Primidone. The full list is on the Ketotifen page.
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