Drug interactions
Levonorgestrel + Tesamorelin
Severity: Minor
Levonorgestrel and Tesamorelin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tesamorelin raises growth hormone and IGF-1, which may alter CYP450 activity, but no reliable evidence shows reduced levonorgestrel effect. The interaction is theoretical.
What this interaction means in plain words
Levonorgestrel and Tesamorelin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible change in CYP3A4 activity via growth hormone and IGF-1; not well established.
What to do
No routine change is required; monitor contraceptive efficacy and bleeding pattern.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levonorgestrel
Frequently asked questions
Can I take Levonorgestrel with Tesamorelin?
MediHelp rates the interaction as minor. Levonorgestrel and Tesamorelin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tesamorelin raises growth hormone and IGF-1, which may alter CYP450 activity, but no reliable evidence shows reduced levonorgestrel effect. The interaction is theoretical.
How serious is the interaction between Levonorgestrel and Tesamorelin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is required; monitor contraceptive efficacy and bleeding pattern.
What other medicines interact with Levonorgestrel?
MediHelp also lists interactions of Levonorgestrel with, for example, Amobarbital, Apalutamide, Belzutifan. The full list is on the Levonorgestrel page.
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