Drug interactions
Levosalbutamol + Pseudoephedrine
Severity: Moderate
Levosalbutamol and Pseudoephedrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are sympathomimetics, so their cardiovascular stimulant effects may add together, causing tachycardia, palpitations, tremor and higher blood pressure. The risk is greater in patients with hypertension, arrhythmias or coronary disease.
What this interaction means in plain words
Levosalbutamol and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levosalbutamol belongs to Respiratory; Pseudoephedrine belongs to Respiratory.
Why it happens
Additive adrenergic stimulation, with direct beta-2 agonism and indirect release of norepinephrine.
What to do
Monitor heart rate and blood pressure and avoid pseudoephedrine in patients with uncontrolled hypertension or cardiac disease. Advise patients to report palpitations or tremor.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Levosalbutamol and Pseudoephedrine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Levosalbutamol
Other interactions of Pseudoephedrine
- Isocarboxazid + Pseudoephedrine Contraindicated
- Phenelzine + Pseudoephedrine Contraindicated
- Pseudoephedrine + Rasagiline Contraindicated
- Pseudoephedrine + Selegiline Contraindicated
- Pseudoephedrine + Selegiline transdermal Contraindicated
- Pseudoephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Levosalbutamol with Pseudoephedrine?
MediHelp rates the interaction as moderate. Levosalbutamol and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are sympathomimetics, so their cardiovascular stimulant effects may add together, causing tachycardia, palpitations, tremor and higher blood pressure. The risk is greater in patients with hypertension, arrhythmias or coronary disease.
How serious is the interaction between Levosalbutamol and Pseudoephedrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure and avoid pseudoephedrine in patients with uncontrolled hypertension or cardiac disease. Advise patients to report palpitations or tremor.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
