Drug interactions
Lidocaine + Papaveretum
Severity: Minor
Lidocaine and Papaveretum: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Papaveretum contains opium alkaloids including morphine, which cause sedation and respiratory depression. Systemic lidocaine may add to this effect.
What this interaction means in plain words
Lidocaine and Papaveretum have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive CNS and respiratory depression.
What to do
Monitor sedation and respiration during systemic lidocaine use and titrate the opioid carefully.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lidocaine
- Bupivacaine liposome + Lidocaine Major
- Disopyramide + Lidocaine Major
- Ex vivo expanded autologous human corneal epithelial cells containing stem cells + Lidocaine Major
- Lidocaine + Nirmatrelvir / ritonavir Major
- Lidocaine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Lidocaine + Pimozide Major
Frequently asked questions
Can I take Lidocaine with Papaveretum?
MediHelp rates the interaction as minor. Lidocaine and Papaveretum have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Papaveretum contains opium alkaloids including morphine, which cause sedation and respiratory depression. Systemic lidocaine may add to this effect.
How serious is the interaction between Lidocaine and Papaveretum?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation and respiration during systemic lidocaine use and titrate the opioid carefully.
What other medicines interact with Lidocaine?
MediHelp also lists interactions of Lidocaine with, for example, Bupivacaine liposome, Disopyramide, Ex vivo expanded autologous human corneal epithelial cells containing stem cells. The full list is on the Lidocaine page.
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