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Drug interactions

Lisinopril + Reishi

Severity: Minor

Lisinopril and Reishi: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Reishi mushroom may have blood pressure lowering properties. With lisinopril the antihypertensive effect could be enhanced, although evidence is limited.

What this interaction means in plain words

Lisinopril and Reishi have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive hypotensive effect; mechanism not well established.

What to do

Monitor blood pressure if reishi is used regularly with lisinopril.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Lisinopril with Reishi?

MediHelp rates the interaction as minor. Lisinopril and Reishi have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reishi mushroom may have blood pressure lowering properties. With lisinopril the antihypertensive effect could be enhanced, although evidence is limited.

How serious is the interaction between Lisinopril and Reishi?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if reishi is used regularly with lisinopril.

What other medicines interact with Lisinopril?

MediHelp also lists interactions of Lisinopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Lisinopril page.

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