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Drug interactions

Lisinopril + Sodium citrate / citric acid

Severity: Minor

Lisinopril and Sodium citrate / citric acid: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

No clinically meaningful interaction is established. Sodium load from the citrate solution is small, and any effect on lisinopril antihypertensive action is theoretical.

What this interaction means in plain words

Lisinopril and Sodium citrate / citric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Not established; possible minor sodium load only.

What to do

No specific action required; monitor blood pressure if used regularly in large amounts.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Lisinopril with Sodium citrate / citric acid?

MediHelp rates the interaction as minor. Lisinopril and Sodium citrate / citric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. No clinically meaningful interaction is established. Sodium load from the citrate solution is small, and any effect on lisinopril antihypertensive action is theoretical.

How serious is the interaction between Lisinopril and Sodium citrate / citric acid?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action required; monitor blood pressure if used regularly in large amounts.

What other medicines interact with Lisinopril?

MediHelp also lists interactions of Lisinopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Lisinopril page.

Full monographs, dosing and an interaction checker in the MediHelp app

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