Drug interactions
Lithium + Sargramostim
Severity: Minor
Lithium and Sargramostim: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lithium raises neutrophil counts and may enhance the myeloproliferative effect of sargramostim, with a possible exaggerated leukocytosis. The clinical consequence is usually modest.
What this interaction means in plain words
Lithium and Sargramostim have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lithium belongs to Central Nervous System; Sargramostim belongs to Miscellaneous.
Why it happens
Additive stimulation of granulopoiesis, as lithium promotes neutrophil production.
What to do
Monitor white blood cell counts during combined use. Adjust sargramostim dosing per standard leukocyte thresholds.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Lithium and Sargramostim, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Lithium
- Lithium + Thioridazine Contraindicated
- Lithium + Vandetanib Contraindicated
- Aceclofenac + Lithium Major
- Acemetacin + Lithium Major
- Amisulpride + Lithium Major
- Amlodipine-benazepril + Lithium Major
Other interactions of Sargramostim
- Ifosfamide + Sargramostim Moderate
- Hydrocortisone + Sargramostim Minor
Frequently asked questions
Can I take Lithium with Sargramostim?
MediHelp rates the interaction as minor. Lithium and Sargramostim have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lithium raises neutrophil counts and may enhance the myeloproliferative effect of sargramostim, with a possible exaggerated leukocytosis. The clinical consequence is usually modest.
How serious is the interaction between Lithium and Sargramostim?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor white blood cell counts during combined use. Adjust sargramostim dosing per standard leukocyte thresholds.
What other medicines interact with Lithium?
MediHelp also lists interactions of Lithium with, for example, Thioridazine, Vandetanib, Aceclofenac. The full list is on the Lithium page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
