Drug interactions
Lithium + Telavancin
Severity: Moderate
Lithium and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lithium can cause QT prolongation and conduction changes, particularly at higher serum levels, and telavancin may add to this. Telavancin-related renal injury could also raise lithium levels, further increasing toxicity risk.
What this interaction means in plain words
Lithium and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lithium belongs to Central Nervous System; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QTc effects, with possible reduced lithium clearance if telavancin causes nephrotoxicity.
What to do
Monitor ECG, serum lithium and renal function during telavancin therapy. Adjust lithium dose if renal function declines.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Lithium
- Lithium + Thioridazine Contraindicated
- Lithium + Vandetanib Contraindicated
- Aceclofenac + Lithium Major
- Acemetacin + Lithium Major
- Amisulpride + Lithium Major
- Amlodipine-benazepril + Lithium Major
Frequently asked questions
Can I take Lithium with Telavancin?
MediHelp rates the interaction as moderate. Lithium and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lithium can cause QT prolongation and conduction changes, particularly at higher serum levels, and telavancin may add to this. Telavancin-related renal injury could also raise lithium levels, further increasing toxicity risk.
How serious is the interaction between Lithium and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, serum lithium and renal function during telavancin therapy. Adjust lithium dose if renal function declines.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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