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Drug interactions

Lorazepam + Motherwort

Severity: Minor

Lorazepam and Motherwort: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Motherwort has traditional sedative properties, so it may add to the drowsiness caused by lorazepam. Clinical data are scarce and the effect is largely predicted.

What this interaction means in plain words

Lorazepam and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive sedative effect of herbal constituents; mechanism not firmly established.

What to do

Advise patients to report additional drowsiness and to avoid driving until the response is known. Consider stopping the herb if sedation is excessive.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Lorazepam with Motherwort?

MediHelp rates the interaction as minor. Lorazepam and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort has traditional sedative properties, so it may add to the drowsiness caused by lorazepam. Clinical data are scarce and the effect is largely predicted.

How serious is the interaction between Lorazepam and Motherwort?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report additional drowsiness and to avoid driving until the response is known. Consider stopping the herb if sedation is excessive.

What other medicines interact with Lorazepam?

MediHelp also lists interactions of Lorazepam with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Lorazepam page.

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