Drug interactions
Lorazepam + Norepinephrine
Severity: Minor
Lorazepam and Norepinephrine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Norepinephrine is an intravenous vasopressor given in critical care, and no meaningful pharmacological interaction with lorazepam is established. Both drugs act independently in sedated critically ill patients.
What this interaction means in plain words
Lorazepam and Norepinephrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established pharmacokinetic or pharmacodynamic interaction.
What to do
No dose change is required. Titrate each drug to its own hemodynamic and sedation targets.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lorazepam
Frequently asked questions
Can I take Lorazepam with Norepinephrine?
MediHelp rates the interaction as minor. Lorazepam and Norepinephrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Norepinephrine is an intravenous vasopressor given in critical care, and no meaningful pharmacological interaction with lorazepam is established. Both drugs act independently in sedated critically ill patients.
How serious is the interaction between Lorazepam and Norepinephrine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is required. Titrate each drug to its own hemodynamic and sedation targets.
What other medicines interact with Lorazepam?
MediHelp also lists interactions of Lorazepam with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Lorazepam page.
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