Drug interactions
Lorazepam + Phenylephrine po
Severity: Minor
Lorazepam and Phenylephrine po: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral phenylephrine is a decongestant with minimal CNS activity and no meaningful interaction with lorazepam is established. Any effect on sedation is not clinically reliable.
What this interaction means in plain words
Lorazepam and Phenylephrine po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established pharmacokinetic or pharmacodynamic interaction.
What to do
No specific action is needed. Reassess if the patient reports unusual drowsiness or palpitations.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lorazepam
Frequently asked questions
Can I take Lorazepam with Phenylephrine po?
MediHelp rates the interaction as minor. Lorazepam and Phenylephrine po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral phenylephrine is a decongestant with minimal CNS activity and no meaningful interaction with lorazepam is established. Any effect on sedation is not clinically reliable.
How serious is the interaction between Lorazepam and Phenylephrine po?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed. Reassess if the patient reports unusual drowsiness or palpitations.
What other medicines interact with Lorazepam?
MediHelp also lists interactions of Lorazepam with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Lorazepam page.
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