Drug interactions
Lorcaserin + Timolol
Severity: Minor
Lorcaserin and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lorcaserin inhibits CYP2D6 and may increase timolol concentrations, possibly strengthening beta-blockade. The clinical significance is likely small with ophthalmic timolol.
What this interaction means in plain words
Lorcaserin and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Inhibition of CYP2D6-mediated timolol metabolism.
What to do
Monitor heart rate and blood pressure and reduce the timolol dose if signs of excessive beta-blockade occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Frequently asked questions
Can I take Lorcaserin with Timolol?
MediHelp rates the interaction as minor. Lorcaserin and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lorcaserin inhibits CYP2D6 and may increase timolol concentrations, possibly strengthening beta-blockade. The clinical significance is likely small with ophthalmic timolol.
How serious is the interaction between Lorcaserin and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure and reduce the timolol dose if signs of excessive beta-blockade occur.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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