Drug interactions
Lovotibeglogene autotemcel + Measles mumps and rubella vaccine
Severity: Moderate
Lovotibeglogene autotemcel and Measles mumps and rubella vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Safety of live viral vaccines has not been studied around lovotibeglogene autotemcel. Myeloablative conditioning leaves a period of immunodeficiency in which live vaccine could cause disease.
What this interaction means in plain words
Lovotibeglogene autotemcel and Measles mumps and rubella vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Myeloablative conditioning and hematopoietic reconstitution cause temporary immunocompromise, raising the risk with live vaccines.
What to do
Defer live vaccines until immune reconstitution is documented, following institutional transplant vaccination guidance.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
Frequently asked questions
Can I take Lovotibeglogene autotemcel with Measles mumps and rubella vaccine?
MediHelp rates the interaction as moderate. Lovotibeglogene autotemcel and Measles mumps and rubella vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Safety of live viral vaccines has not been studied around lovotibeglogene autotemcel. Myeloablative conditioning leaves a period of immunodeficiency in which live vaccine could cause disease.
How serious is the interaction between Lovotibeglogene autotemcel and Measles mumps and rubella vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer live vaccines until immune reconstitution is documented, following institutional transplant vaccination guidance.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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