Drug interactions
Maitake + Nateglinide
Severity: Minor
Maitake and Nateglinide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maitake mushroom extracts have lowered blood glucose in animal studies, so they might add to the glucose-lowering effect of nateglinide. Human evidence is scarce.
What this interaction means in plain words
Maitake and Nateglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive pharmacodynamic hypoglycemic effect, based on animal data; not established in humans.
What to do
Monitor blood glucose if maitake supplements are used regularly with nateglinide. Reduce the nateglinide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nateglinide
- Albiglutide + Nateglinide Moderate
- Alogliptin-metformin + Nateglinide Moderate
- Alogliptin-pioglitazone + Nateglinide Moderate
- Alogliptin + Nateglinide Moderate
- Alpelisib + Nateglinide Moderate
- Amiodarone + Nateglinide Moderate
Frequently asked questions
Can I take Maitake with Nateglinide?
MediHelp rates the interaction as minor. Maitake and Nateglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom extracts have lowered blood glucose in animal studies, so they might add to the glucose-lowering effect of nateglinide. Human evidence is scarce.
How serious is the interaction between Maitake and Nateglinide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if maitake supplements are used regularly with nateglinide. Reduce the nateglinide dose if hypoglycemia occurs.
What other medicines interact with Nateglinide?
MediHelp also lists interactions of Nateglinide with, for example, Albiglutide, Alogliptin-metformin, Alogliptin-pioglitazone. The full list is on the Nateglinide page.
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