Drug interactions
Mavacamten + Telmisartan
Severity: Minor
Mavacamten and Telmisartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Telmisartan is not an established CYP2C19 inhibitor, so a meaningful rise in mavacamten levels is unlikely. Mavacamten itself requires careful monitoring of ejection fraction.
What this interaction means in plain words
Mavacamten and Telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Mavacamten belongs to Cardiovascular; Telmisartan belongs to Cardiovascular.
Why it happens
Weak, theoretical CYP2C19 inhibition by telmisartan; not clinically established.
What to do
No dose change is needed; follow standard mavacamten echocardiographic monitoring.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Other interactions of Mavacamten
- Apalutamide + Mavacamten Contraindicated
- Carbamazepine + Mavacamten Contraindicated
- Clarithromycin + Mavacamten Contraindicated
- Dexlansoprazole + Mavacamten Contraindicated
- Efavirenz + Mavacamten Contraindicated
- Enzalutamide + Mavacamten Contraindicated
Frequently asked questions
Can I take Mavacamten with Telmisartan?
MediHelp rates the interaction as minor. Mavacamten and Telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Telmisartan is not an established CYP2C19 inhibitor, so a meaningful rise in mavacamten levels is unlikely. Mavacamten itself requires careful monitoring of ejection fraction.
How serious is the interaction between Mavacamten and Telmisartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; follow standard mavacamten echocardiographic monitoring.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
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