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Drug interactions

Measles mumps and rubella vaccine + Risankizumab

Severity: Moderate

Measles mumps and rubella vaccine and Risankizumab: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Risankizumab is an IL-23 inhibitor, and live vaccines are advised against during treatment because of theoretical risk of vaccine-strain infection. Vaccine response data are limited.

What this interaction means in plain words

Measles mumps and rubella vaccine and Risankizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Measles mumps and rubella vaccine belongs to Miscellaneous; Risankizumab belongs to Miscellaneous.

Evidence level: Low

Why it happens

IL-23 inhibition modulates cellular immunity, possibly reducing control of live attenuated virus; risk is theoretical.

What to do

Complete MMR before starting risankizumab where possible; avoid live vaccines during therapy.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Measles mumps and rubella vaccine with Risankizumab?

MediHelp rates the interaction as moderate. Measles mumps and rubella vaccine and Risankizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Risankizumab is an IL-23 inhibitor, and live vaccines are advised against during treatment because of theoretical risk of vaccine-strain infection. Vaccine response data are limited.

How serious is the interaction between Measles mumps and rubella vaccine and Risankizumab?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete MMR before starting risankizumab where possible; avoid live vaccines during therapy.

What other medicines interact with Measles mumps and rubella vaccine?

MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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