Drug interactions
Measles mumps and rubella vaccine + Tildrakizumab
Severity: Major
Measles mumps and rubella vaccine and Tildrakizumab: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tildrakizumab is an IL-23 p19 inhibitor that modulates immune function. Live vaccines in patients on this drug could cause vaccine-strain infection, and there are no data on how well vaccines work during therapy.
What this interaction means in plain words
Measles mumps and rubella vaccine and Tildrakizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Measles mumps and rubella vaccine belongs to Miscellaneous; Tildrakizumab belongs to Miscellaneous.
Why it happens
Pharmacodynamic: IL-23 inhibition may weaken immune control of replicating live vaccine viruses.
What to do
Avoid live vaccines during tildrakizumab therapy. Complete age-appropriate immunizations, including live vaccines, before starting treatment.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
Frequently asked questions
Can I take Measles mumps and rubella vaccine with Tildrakizumab?
MediHelp rates the interaction as major. Measles mumps and rubella vaccine and Tildrakizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Tildrakizumab is an IL-23 p19 inhibitor that modulates immune function. Live vaccines in patients on this drug could cause vaccine-strain infection, and there are no data on how well vaccines work during therapy.
How serious is the interaction between Measles mumps and rubella vaccine and Tildrakizumab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during tildrakizumab therapy. Complete age-appropriate immunizations, including live vaccines, before starting treatment.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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