Drug interactions
Meloxicam + Pau d'arco
Severity: Moderate
Meloxicam and Pau d'arco: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pau d'arco contains naphthoquinones such as lapachol, which may have anti-vitamin K activity and affect coagulation. Taken with meloxicam, the bleeding risk could rise, but evidence is limited to theoretical concerns.
What this interaction means in plain words
Meloxicam and Pau d'arco can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive effects on hemostasis (vitamin K antagonism by constituents plus NSAID platelet inhibition).
What to do
Avoid combining where possible and monitor for bleeding if both are used. Review for other anticoagulants.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Meloxicam and Pau d'arco, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Meloxicam
- Ketorolac intranasal + Meloxicam Contraindicated
- Ketorolac + Meloxicam Contraindicated
- Aceclofenac + Meloxicam Major
- Acemetacin + Meloxicam Major
- Acetylsalicylic acid + Meloxicam Major
- Alteplase + Meloxicam Major
Frequently asked questions
Can I take Meloxicam with Pau d'arco?
MediHelp rates the interaction as moderate. Meloxicam and Pau d'arco can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pau d'arco contains naphthoquinones such as lapachol, which may have anti-vitamin K activity and affect coagulation. Taken with meloxicam, the bleeding risk could rise, but evidence is limited to theoretical concerns.
How serious is the interaction between Meloxicam and Pau d'arco?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible and monitor for bleeding if both are used. Review for other anticoagulants.
What other medicines interact with Meloxicam?
MediHelp also lists interactions of Meloxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meloxicam page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
