Drug interactions
Meningococcal group b vaccine + Vinorelbine
Severity: Moderate
Meningococcal group b vaccine and Vinorelbine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chemotherapy-related immunosuppression may reduce antibody responses to meningococcal B vaccine. Protection may be incomplete.
What this interaction means in plain words
Meningococcal group b vaccine and Vinorelbine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Chemotherapy-induced myelosuppression blunts vaccine immune response.
What to do
Vaccinate before chemotherapy when feasible or after count recovery. Consider checking response or revaccination where indicated.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Vinorelbine
Frequently asked questions
Can I take Meningococcal group b vaccine with Vinorelbine?
MediHelp rates the interaction as moderate. Meningococcal group b vaccine and Vinorelbine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chemotherapy-related immunosuppression may reduce antibody responses to meningococcal B vaccine. Protection may be incomplete.
How serious is the interaction between Meningococcal group b vaccine and Vinorelbine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before chemotherapy when feasible or after count recovery. Consider checking response or revaccination where indicated.
What other medicines interact with Vinorelbine?
MediHelp also lists interactions of Vinorelbine with, for example, Adenovirus types 4 and 7 live, Apalutamide, Belatacept. The full list is on the Vinorelbine page.
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