Drug interactions
Mestranol + Ropinirole
Severity: Minor
Mestranol and Ropinirole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mestranol is converted to ethinylestradiol, and estrogens of this type may raise ropinirole exposure. Dopaminergic adverse effects such as nausea, somnolence or orthostatic hypotension could be more noticeable.
What this interaction means in plain words
Mestranol and Ropinirole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Probable reduced CYP1A2-mediated clearance of ropinirole by ethinylestradiol-type estrogens.
What to do
No routine change is needed. Adjust the ropinirole dose if adverse effects occur after the estrogen is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ropinirole
- Amisulpride + Ropinirole Contraindicated
- Chlorpromazine + Ropinirole Major
- Droperidol + Ropinirole Major
- Fluphenazine + Ropinirole Major
- Fluvoxamine + Ropinirole Major
- Haloperidol + Ropinirole Major
Frequently asked questions
Can I take Mestranol with Ropinirole?
MediHelp rates the interaction as minor. Mestranol and Ropinirole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Mestranol is converted to ethinylestradiol, and estrogens of this type may raise ropinirole exposure. Dopaminergic adverse effects such as nausea, somnolence or orthostatic hypotension could be more noticeable.
How serious is the interaction between Mestranol and Ropinirole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Adjust the ropinirole dose if adverse effects occur after the estrogen is started or stopped.
What other medicines interact with Ropinirole?
MediHelp also lists interactions of Ropinirole with, for example, Amisulpride, Chlorpromazine, Droperidol. The full list is on the Ropinirole page.
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