Drug interactions
Metaproterenol + Triamterene
Severity: Minor
Metaproterenol and Triamterene: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Metaproterenol can lower serum potassium through intracellular shift, which counters the potassium-raising effect of triamterene. The net effect is unpredictable but rarely clinically important.
What this interaction means in plain words
Metaproterenol and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Beta-2 agonist-driven cellular potassium uptake opposes triamterene-induced potassium retention.
What to do
No routine action is needed; monitor potassium if high doses of metaproterenol are used or renal function is impaired.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Triamterene
- Amiloride + Triamterene Contraindicated
- Eplerenone + Triamterene Contraindicated
- Potassium citrate / citric acid + Triamterene Contraindicated
- Potassium citrate + Triamterene Contraindicated
- Spironolactone + Triamterene Contraindicated
- Aceclofenac + Triamterene Major
Frequently asked questions
Can I take Metaproterenol with Triamterene?
MediHelp rates the interaction as minor. Metaproterenol and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Metaproterenol can lower serum potassium through intracellular shift, which counters the potassium-raising effect of triamterene. The net effect is unpredictable but rarely clinically important.
How serious is the interaction between Metaproterenol and Triamterene?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor potassium if high doses of metaproterenol are used or renal function is impaired.
What other medicines interact with Triamterene?
MediHelp also lists interactions of Triamterene with, for example, Amiloride, Eplerenone, Potassium citrate / citric acid. The full list is on the Triamterene page.
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