Drug interactions
Metformin + Moexipril
Severity: Minor
Metformin and Moexipril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors may slightly enhance glucose lowering when combined with metformin, though metformin alone seldom causes hypoglycemia. ACE inhibitor-related renal function decline can reduce metformin clearance and increase lactic acidosis risk.
What this interaction means in plain words
Metformin and Moexipril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Metformin belongs to Endocrine; Moexipril belongs to Cardiovascular.
Why it happens
Possible improved insulin sensitivity with ACE inhibition and reduced renal metformin elimination if renal function declines.
What to do
Monitor glucose and renal function periodically after starting moexipril. Reassess metformin dosing if renal function declines.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Metformin and Moexipril, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Other interactions of Metformin
Frequently asked questions
Can I take Metformin with Moexipril?
MediHelp rates the interaction as minor. Metformin and Moexipril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. ACE inhibitors may slightly enhance glucose lowering when combined with metformin, though metformin alone seldom causes hypoglycemia. ACE inhibitor-related renal function decline can reduce metformin clearance and increase lactic acidosis risk.
How serious is the interaction between Metformin and Moexipril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose and renal function periodically after starting moexipril. Reassess metformin dosing if renal function declines.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
