Drug interactions
Metformin-repaglinide + Norgestimate
Severity: Minor
Metformin-repaglinide and Norgestimate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Norgestimate, usually combined with ethinyl estradiol, may slightly impair glucose tolerance. Clinically important effects on diabetes control are uncommon with low-dose products.
What this interaction means in plain words
Metformin-repaglinide and Norgestimate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Estrogen and progestin effects can mildly reduce insulin sensitivity.
What to do
Monitor blood glucose when starting the contraceptive and adjust antidiabetic therapy only if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-repaglinide
Frequently asked questions
Can I take Metformin-repaglinide with Norgestimate?
MediHelp rates the interaction as minor. Metformin-repaglinide and Norgestimate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Norgestimate, usually combined with ethinyl estradiol, may slightly impair glucose tolerance. Clinically important effects on diabetes control are uncommon with low-dose products.
How serious is the interaction between Metformin-repaglinide and Norgestimate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting the contraceptive and adjust antidiabetic therapy only if control worsens.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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