Drug interactions
Metformin-repaglinide + Oxandrolone
Severity: Moderate
Metformin-repaglinide and Oxandrolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anabolic steroids can lower blood glucose and may enhance the effect of antidiabetic drugs, increasing hypoglycemia risk, particularly with repaglinide.
What this interaction means in plain words
Metformin-repaglinide and Oxandrolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Anabolic steroids may enhance insulin sensitivity, adding to the glucose-lowering effect.
What to do
Monitor blood glucose when oxandrolone is started or stopped, and reduce the repaglinide dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Metformin-repaglinide and Oxandrolone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Metformin-repaglinide
Frequently asked questions
Can I take Metformin-repaglinide with Oxandrolone?
MediHelp rates the interaction as moderate. Metformin-repaglinide and Oxandrolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anabolic steroids can lower blood glucose and may enhance the effect of antidiabetic drugs, increasing hypoglycemia risk, particularly with repaglinide.
How serious is the interaction between Metformin-repaglinide and Oxandrolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when oxandrolone is started or stopped, and reduce the repaglinide dose if hypoglycemia occurs.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
