Drug interactions
Metformin-repaglinide + Oxymetholone
Severity: Moderate
Metformin-repaglinide and Oxymetholone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anabolic steroids can lower blood glucose and may enhance the effect of antidiabetic drugs, increasing hypoglycemia risk, particularly with repaglinide.
What this interaction means in plain words
Metformin-repaglinide and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Anabolic steroids may enhance insulin sensitivity, adding to the glucose-lowering effect.
What to do
Monitor blood glucose when oxymetholone is started or stopped, and reduce the repaglinide dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Metformin-repaglinide
Frequently asked questions
Can I take Metformin-repaglinide with Oxymetholone?
MediHelp rates the interaction as moderate. Metformin-repaglinide and Oxymetholone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anabolic steroids can lower blood glucose and may enhance the effect of antidiabetic drugs, increasing hypoglycemia risk, particularly with repaglinide.
How serious is the interaction between Metformin-repaglinide and Oxymetholone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when oxymetholone is started or stopped, and reduce the repaglinide dose if hypoglycemia occurs.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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