Drug interactions
Metformin-repaglinide + Shark cartilage
Severity: Minor
Metformin-repaglinide and Shark cartilage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shark cartilage has been theorized to affect glucose levels and add to the effect of antidiabetic drugs. Supporting clinical evidence is lacking.
What this interaction means in plain words
Metformin-repaglinide and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mechanism is not established; a theoretical additive glucose-lowering effect has been proposed.
What to do
Advise patients to report supplement use and monitor blood glucose if they take it.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-repaglinide
Frequently asked questions
Can I take Metformin-repaglinide with Shark cartilage?
MediHelp rates the interaction as minor. Metformin-repaglinide and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shark cartilage has been theorized to affect glucose levels and add to the effect of antidiabetic drugs. Supporting clinical evidence is lacking.
How serious is the interaction between Metformin-repaglinide and Shark cartilage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report supplement use and monitor blood glucose if they take it.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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