Drug interactions
Methyl aminolevulinate + Tetracycline
Severity: Moderate
Methyl aminolevulinate and Tetracycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetracyclines are photosensitizing and methyl aminolevulinate is used with light for photodynamic therapy. Together they may increase skin phototoxicity such as burning, redness and pain after illumination.
What this interaction means in plain words
Methyl aminolevulinate and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive photosensitizing effects of the two agents.
What to do
Consider delaying photodynamic therapy until systemic tetracycline is finished, or monitor closely for exaggerated phototoxic reactions. Advise strict sun protection.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tetracycline
- Acitretin + Tetracycline Contraindicated
- Methoxyflurane + Tetracycline Contraindicated
- Isotretinoin + Tetracycline Major
- Palovarotene + Tetracycline Major
- Strontium ranelate + Tetracycline Major
- Tetracycline + Tretinoin Major
Frequently asked questions
Can I take Methyl aminolevulinate with Tetracycline?
MediHelp rates the interaction as moderate. Methyl aminolevulinate and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tetracyclines are photosensitizing and methyl aminolevulinate is used with light for photodynamic therapy. Together they may increase skin phototoxicity such as burning, redness and pain after illumination.
How serious is the interaction between Methyl aminolevulinate and Tetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider delaying photodynamic therapy until systemic tetracycline is finished, or monitor closely for exaggerated phototoxic reactions. Advise strict sun protection.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.
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