Drug interactions
Methyl aminolevulinate + Tolmetin
Severity: Minor
Methyl aminolevulinate and Tolmetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Methyl aminolevulinate is used with light in photodynamic therapy and drugs that cause photosensitivity may amplify skin reactions. NSAIDs can occasionally cause photosensitivity. Systemic exposure from topical methyl aminolevulinate is low, so the interaction is mostly theoretical.
What this interaction means in plain words
Methyl aminolevulinate and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive photosensitization in treated skin.
What to do
Review other photosensitizing drugs before photodynamic therapy and monitor the treated area for exaggerated erythema or pain. Continued NSAID use is generally acceptable if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Methyl aminolevulinate and Tolmetin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Frequently asked questions
Can I take Methyl aminolevulinate with Tolmetin?
MediHelp rates the interaction as minor. Methyl aminolevulinate and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Methyl aminolevulinate is used with light in photodynamic therapy and drugs that cause photosensitivity may amplify skin reactions. NSAIDs can occasionally cause photosensitivity. Systemic exposure from topical methyl aminolevulinate is low, so the interaction is mostly theoretical.
How serious is the interaction between Methyl aminolevulinate and Tolmetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Review other photosensitizing drugs before photodynamic therapy and monitor the treated area for exaggerated erythema or pain. Continued NSAID use is generally acceptable if needed.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
