Drug interactions
Metoclopramide intranasal + Oxcarbazepine
Severity: Minor
Metoclopramide intranasal and Oxcarbazepine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause CNS effects such as somnolence, and metoclopramide can cause extrapyramidal reactions. A clear pharmacokinetic interaction is not established. Additive CNS effects and neurological adverse events are possible.
What this interaction means in plain words
Metoclopramide intranasal and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS effects; no well-established mechanism.
What to do
Monitor for drowsiness, dizziness and movement disorders, and counsel patients on driving.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxcarbazepine
- Cabotegravir + Oxcarbazepine Contraindicated
- Oxcarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Oxcarbazepine Major
- Atazanavir + Oxcarbazepine Major
- Benzhydrocodone / acetaminophen + Oxcarbazepine Major
- Bictegravir + Oxcarbazepine Major
Frequently asked questions
Can I take Metoclopramide intranasal with Oxcarbazepine?
MediHelp rates the interaction as minor. Metoclopramide intranasal and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause CNS effects such as somnolence, and metoclopramide can cause extrapyramidal reactions. A clear pharmacokinetic interaction is not established. Additive CNS effects and neurological adverse events are possible.
How serious is the interaction between Metoclopramide intranasal and Oxcarbazepine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for drowsiness, dizziness and movement disorders, and counsel patients on driving.
What other medicines interact with Oxcarbazepine?
MediHelp also lists interactions of Oxcarbazepine with, for example, Cabotegravir, Rilpivirine, Artemether / lumefantrine. The full list is on the Oxcarbazepine page.
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