Drug interactions
Microbiota + Telavancin
Severity: Moderate
Microbiota and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral microbiota products contain live bacterial spores that need to colonize the gut. Telavancin is a systemic antibiotic and could reduce the viability of the product, which may lower its effectiveness in preventing recurrent C. difficile infection.
What this interaction means in plain words
Microbiota and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Antibacterial activity may reduce engraftment of the live bacterial product (pharmacodynamic antagonism).
What to do
Complete the antibiotic course and allow a washout interval of a few days, as the product labeling advises, before giving the microbiota product.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Frequently asked questions
Can I take Microbiota with Telavancin?
MediHelp rates the interaction as moderate. Microbiota and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral microbiota products contain live bacterial spores that need to colonize the gut. Telavancin is a systemic antibiotic and could reduce the viability of the product, which may lower its effectiveness in preventing recurrent C. difficile infection.
How serious is the interaction between Microbiota and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete the antibiotic course and allow a washout interval of a few days, as the product labeling advises, before giving the microbiota product.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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