Skip to content

Drug interactions

Moexipril + Potassium citrate-citric acid

Severity: Moderate

Moexipril and Potassium citrate-citric acid: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Moexipril decreases aldosterone-mediated potassium excretion and potassium citrate adds a potassium load. Hyperkalemia is possible, especially when kidney function is reduced.

What this interaction means in plain words

Moexipril and Potassium citrate-citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Moexipril belongs to Cardiovascular; Potassium citrate-citric acid belongs to Gastrointestinal Tract.

Evidence level: High

Why it happens

ACE inhibition reduces aldosterone and renal potassium excretion, compounding the exogenous potassium.

What to do

Monitor serum potassium and renal function at baseline and regularly. Reduce or stop the potassium supplement if levels rise.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to unlock the full management advice for Moexipril and Potassium citrate-citric acid, the additional notes, the evidence detail and the whole-prescription interaction checker.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Try Pro+ free for 7 days on the web. No card needed.

Frequently asked questions

Can I take Moexipril with Potassium citrate-citric acid?

MediHelp rates the interaction as moderate. Moexipril and Potassium citrate-citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Moexipril decreases aldosterone-mediated potassium excretion and potassium citrate adds a potassium load. Hyperkalemia is possible, especially when kidney function is reduced.

How serious is the interaction between Moexipril and Potassium citrate-citric acid?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function at baseline and regularly. Reduce or stop the potassium supplement if levels rise.

What other medicines interact with Potassium citrate-citric acid?

MediHelp also lists interactions of Potassium citrate-citric acid with, for example, Amiloride, Eplerenone, Finerenone. The full list is on the Potassium citrate-citric acid page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in