Drug interactions
Moexipril + Sodium sulfate / ?magnesium sulfate / potassium chloride
Severity: Moderate
Moexipril and Sodium sulfate / ?magnesium sulfate / potassium chloride: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bowel preparations containing sulfate salts and potassium cause fluid shifts and electrolyte disturbances. In a patient taking an ACE inhibitor, volume depletion and added potassium load can precipitate acute kidney injury and hyperkalemia.
What this interaction means in plain words
Moexipril and Sodium sulfate / ?magnesium sulfate / potassium chloride can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Bowel-prep-induced volume depletion and potassium load combine with ACE inhibitor reduction of glomerular filtration pressure and aldosterone-mediated potassium excretion.
What to do
Ensure adequate hydration and consider withholding moexipril on the day of bowel preparation in high-risk patients. Check renal function and potassium afterwards if risk factors exist.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Frequently asked questions
Can I take Moexipril with Sodium sulfate / ?magnesium sulfate / potassium chloride?
MediHelp rates the interaction as moderate. Moexipril and Sodium sulfate / ?magnesium sulfate / potassium chloride can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bowel preparations containing sulfate salts and potassium cause fluid shifts and electrolyte disturbances. In a patient taking an ACE inhibitor, volume depletion and added potassium load can precipitate acute kidney injury and hyperkalemia.
How serious is the interaction between Moexipril and Sodium sulfate / ?magnesium sulfate / potassium chloride?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure adequate hydration and consider withholding moexipril on the day of bowel preparation in high-risk patients. Check renal function and potassium afterwards if risk factors exist.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
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