Drug interactions
Moexipril + Sodium sulfate / potassium sulfate / magnesium sulfate
Severity: Moderate
Moexipril and Sodium sulfate / potassium sulfate / magnesium sulfate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sulfate-based bowel preparations can cause significant fluid loss and electrolyte shifts. With an ACE inhibitor, volume depletion raises the risk of acute kidney injury, and potassium content may contribute to hyperkalemia.
What this interaction means in plain words
Moexipril and Sodium sulfate / potassium sulfate / magnesium sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Osmotic fluid loss and electrolyte changes combine with ACE inhibitor dependence of renal perfusion on angiotensin II.
What to do
Encourage adequate fluid intake and consider holding moexipril on the preparation day in patients with renal impairment or elderly. Monitor renal function and electrolytes if symptoms or risk factors are present.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Frequently asked questions
Can I take Moexipril with Sodium sulfate / potassium sulfate / magnesium sulfate?
MediHelp rates the interaction as moderate. Moexipril and Sodium sulfate / potassium sulfate / magnesium sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sulfate-based bowel preparations can cause significant fluid loss and electrolyte shifts. With an ACE inhibitor, volume depletion raises the risk of acute kidney injury, and potassium content may contribute to hyperkalemia.
How serious is the interaction between Moexipril and Sodium sulfate / potassium sulfate / magnesium sulfate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Encourage adequate fluid intake and consider holding moexipril on the preparation day in patients with renal impairment or elderly. Monitor renal function and electrolytes if symptoms or risk factors are present.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
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