Drug interactions
Mometasone inhaled + Ofloxacin
Severity: Minor
Mometasone inhaled and Ofloxacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluoroquinolones carry a risk of tendinitis and tendon rupture that is increased by systemic corticosteroids. With inhaled mometasone, systemic exposure is low, so the added risk is small.
What this interaction means in plain words
Mometasone inhaled and Ofloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive tendon toxicity; corticosteroids impair collagen turnover while fluoroquinolones damage tenocytes.
What to do
Counsel the patient to stop ofloxacin and report tendon pain or swelling promptly. Take extra care in older patients or those also on systemic steroids.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ofloxacin
- Ofloxacin + Thioridazine Contraindicated
- Adagrasib + Ofloxacin Major
- Amiodarone + Ofloxacin Major
- Amisulpride + Ofloxacin Major
- Anagrelide + Ofloxacin Major
- Arsenic trioxide + Ofloxacin Major
Frequently asked questions
Can I take Mometasone inhaled with Ofloxacin?
MediHelp rates the interaction as minor. Mometasone inhaled and Ofloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluoroquinolones carry a risk of tendinitis and tendon rupture that is increased by systemic corticosteroids. With inhaled mometasone, systemic exposure is low, so the added risk is small.
How serious is the interaction between Mometasone inhaled and Ofloxacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to stop ofloxacin and report tendon pain or swelling promptly. Take extra care in older patients or those also on systemic steroids.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
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